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Peptide Atlas · Vitamin

Pyridoxine hydrochloride

High daily doses of pyridoxine (vitamin B6) caused ataxia and severe sensory neuropathy in seven adults, all of whom improved after stopping it.

What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

  • created page created as 'Pyridoxine hydrochloride' with aliases Pyridoxine HCl, Vitamin B6 hydrochloride, Pyridoxol hydrochloride, Adermine hydrochloride · 2026-09-27 12:04 · somebody
  • kind set kind set to vitamin: palette r2 · 2026-09-27 12:04 · somebody
  • fact added identity: PubChem CID 6019: Pyridoxine Hydrochloride, C8H12ClNO3, 205.64 g/mol. · 2026-09-27 12:04 · somebody
  • fact added identity: CAS registry number 58-56-0. · 2026-09-27 12:04 · somebody
  • fact added identity: IUPAC name: 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol;hydrochloride. · 2026-09-27 12:04 · somebody
  • fact added summary: High daily doses of pyridoxine (vitamin B6) caused ataxia and severe sensory neuropathy in seven adults, all of whom imp · 2026-09-27 12:04 · somebody
  • fact added summary: Pyridoxine-dependent seizures are a rare disorder in which seizures, usually beginning in newborns, respond to pyridoxin · 2026-09-27 12:04 · somebody
  • citation added pmid 6308447 cited as established: Sensory neuropathy from high-dose pyridoxine (case series) · 2026-09-27 12:04 · somebody
  • citation added pmid 18762976 cited as emerging: Registry of 63 cases of pyridoxine-dependent and -responsive seizures · 2026-09-27 12:04 · somebody

Negative findings

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