Peptide Atlas · Excipient

Sodium Citrate Tribasic

Citrate is a common buffer in injectable biologics; a systematic review found that five of seven direct comparisons reported less injection-site pain with citrate-free formulations.

emerging

provisional
PubChem 71474
2 citations
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Citrate
Trisodium citrate dihydrate

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What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- emerging
  Claim: Systematic review: injection-site pain and citrate standing
- resolved
A Systematic Literature Review of Injection Site Pain Perception in Adult Patients Treated with Citrate-Free and Citrate-Containing Biologic Agents.
Junker S, Ebert O, Bartsch R
pmid 36043729
- emerging
  Claim: Volume and citrate in perceived pain with adalimumab standing
- resolved
Influence of volume and citrate on perceived pain in patients treated with adalimumab.
Misa-Garcia A, Ferro-Rodríguez S, Haro-Martín L, Cavero-Redondo I
pmid 39890432

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Negative findings

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