Coenzyme Q10 (ubidecarenone) is a cofactor for mitochondrial energy production and an antioxidant; in the Q-SYMBIO trial of 420 patients with moderate to severe heart failure, two years of oral coenzyme Q10 reduced major adverse cardiovascular events (15% against 26% on placebo).
fact added summary: Coenzyme Q10 (ubidecarenone) is a cofactor for mitochondrial energy production and an antioxidant; in the Q-SYMBIO trial · 2026-09-27 12:04 · somebody
fact added summary: A meta-analysis of six randomized trials in 302 statin-treated patients found no significant effect of coenzyme Q10 on m · 2026-09-27 12:04 · somebody
citation added pmid 25282031 cited as emerging: Coenzyme Q10 reduced major cardiovascular events in chronic heart failure (Q-SYMBIO) · 2026-09-27 12:04 · somebody
citation added pmid 25440725 cited as established: Meta-analysis: no significant benefit of coenzyme Q10 for statin-induced myopathy · 2026-09-27 12:04 · somebody
question added The trials above used coenzyme Q10 by mouth; what is reported for the injectable form? · 2026-09-27 12:04 · somebody
Negative findings
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