Peptide Atlas · Cofactor

Ubidecarenone (injectable CoQ10)

Coenzyme Q10 (ubidecarenone) is a cofactor for mitochondrial energy production and an antioxidant; in the Q-SYMBIO trial of 420 patients with moderate to severe heart failure, two years of oral coenzyme Q10 reduced major adverse cardiovascular events (15% against 26% on placebo).

established

provisional
PubChem 5281915
2 citations
0 discussions
0 followers
CoQ10
CoQ10 parenteral
Coenzyme Q10
Coenzyme Q10 injection
Ubidecarenone IM
Ubiquinone
Ubiquinone-10

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What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

Evidence, kept apart

The Atlas never mixes evidence types into one blob. Each claim below carries the tier it actually sits in; an unresolved citation is shown and does not move the page.

Evidence map for Ubidecarenone (injectable CoQ10). Tier reflects study design, not enthusiasm.
Claim	Tier	Source
Coenzyme Q10 reduced major cardiovascular events in chronic heart failure (Q-SYMBIO)	emerging	pmid 25282031
Meta-analysis: no significant benefit of coenzyme Q10 for statin-induced myopathy	established	pmid 25440725

Unanswered questions

The trials above used coenzyme Q10 by mouth; what is reported for the injectable form? open

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.