Peptide Atlas · Cofactor

Ubidecarenone (injectable CoQ10)

Coenzyme Q10 (ubidecarenone) is a cofactor for mitochondrial energy production and an antioxidant; in the Q-SYMBIO trial of 420 patients with moderate to severe heart failure, two years of oral coenzyme Q10 reduced major adverse cardiovascular events (15% against 26% on placebo).

established

provisional
PubChem 5281915
2 citations
0 discussions
0 followers
CoQ10
CoQ10 parenteral
Coenzyme Q10
Coenzyme Q10 injection
Ubidecarenone IM
Ubiquinone
Ubiquinone-10

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What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- emerging
  Claim: Coenzyme Q10 reduced major cardiovascular events in chronic heart failure (Q-SYMBIO) standing
- resolved
The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double-blind trial.
Mortensen SA, Rosenfeldt F, Kumar A, Dolliner P, Filipiak KJ, Pella D, Alehagen U, Steurer G, Littarru GP, Q-SYMBIO Study Investigators
pmid 25282031
- established
  Claim: Meta-analysis: no significant benefit of coenzyme Q10 for statin-induced myopathy standing
- resolved
Effects of coenzyme Q10 on statin-induced myopathy: a meta-analysis of randomized controlled trials.
Banach M, Serban C, Sahebkar A, Ursoniu S, Rysz J, Muntner P, Toth PP, Jones SR, Rizzo M, Glasser SP, Lip GY, Dragan S, Mikhailidis DP, Lipid and Blood Pressure Meta-analysis Collaboration Group
pmid 25440725

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

failure is information

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