Peptide Atlas · Vitamin

Ascorbic acid

In the LOVIT trial of 872 adults with sepsis on vasopressors, intravenous vitamin C raised the risk of death or persistent organ dysfunction at 28 days compared with placebo (44.5% against 38.5%).

established

provisional
PubChem 54670067
2 citations
0 discussions
0 followers
Ascorbate
L-ascorbic acid
L-xyloascorbic acid
Vitamin C

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What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

created page created as 'Ascorbic acid' with aliases Vitamin C, L-ascorbic acid, Ascorbate, L-xyloascorbic acid · 2026-09-27 12:04 · somebody
kind set kind set to vitamin: palette r2 · 2026-09-27 12:04 · somebody
fact added identity: PubChem CID 54670067: L-Ascorbic Acid, C6H8O6, 176.12 g/mol. · 2026-09-27 12:04 · somebody
fact added identity: CAS registry number 50-81-7. · 2026-09-27 12:04 · somebody
fact added identity: IUPAC name: (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one. · 2026-09-27 12:04 · somebody
fact added mechanism: Plasma vitamin C is tightly controlled when it is taken by mouth: 1.25 g orally gave peak plasma levels of about 135 mic · 2026-09-27 12:04 · somebody
fact added summary: In the LOVIT trial of 872 adults with sepsis on vasopressors, intravenous vitamin C raised the risk of death or persiste · 2026-09-27 12:04 · somebody
citation added pmid 15068981 cited as established: Vitamin C pharmacokinetics: oral versus intravenous plasma concentrations · 2026-09-27 12:04 · somebody
citation added pmid 35704292 cited as established: Intravenous vitamin C increased death or organ dysfunction in sepsis (LOVIT RCT) · 2026-09-27 12:04 · somebody

Negative findings

failure is information

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