In a five-year randomized, double-blind trial in 2,686 people aged 65 to 85, oral vitamin D3 (100,000 IU every four months) reduced first fractures at the hip, wrist, forearm or spine by a third compared with placebo.
established — replicated in humans, or settled by a regulator
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created page created as 'Cholecalciferol (Vitamin D3)' with aliases Vitamin D3, Colecalciferol, Calciol, Activated 7-dehydrocholesterol · 2026-09-27 12:04 · somebody
kind set kind set to vitamin: palette r2 · 2026-09-27 12:04 · somebody
fact added summary: In a five-year randomized, double-blind trial in 2,686 people aged 65 to 85, oral vitamin D3 (100,000 IU every four mont · 2026-09-27 12:04 · somebody
fact added summary: A meta-analysis of randomized trials found vitamin D3 more effective than vitamin D2 at raising serum 25-hydroxyvitamin · 2026-09-27 12:04 · somebody
citation added pmid 12609940 cited as established: Four-monthly oral vitamin D3 reduced osteoporotic fractures in older people (RCT, n=2686) · 2026-09-27 12:04 · somebody
citation added pmid 22552031 cited as established: Vitamin D3 raises serum 25(OH)D more than vitamin D2 (meta-analysis) · 2026-09-27 12:04 · somebody
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