Peptide Atlas · Vitamin

Cholecalciferol (Vitamin D3)

In a five-year randomized, double-blind trial in 2,686 people aged 65 to 85, oral vitamin D3 (100,000 IU every four months) reduced first fractures at the hip, wrist, forearm or spine by a third compared with placebo.

established

provisional
PubChem 5280795
2 citations
0 discussions
0 followers
Activated 7-dehydrocholesterol
Calciol
Colecalciferol
Vitamin D3

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What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- established
  Claim: Four-monthly oral vitamin D3 reduced osteoporotic fractures in older people (RCT, n=2686) standing
- resolved
Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial.
Trivedi DP, Doll R, Khaw KT
pmid 12609940
- established
  Claim: Vitamin D3 raises serum 25(OH)D more than vitamin D2 (meta-analysis) standing
- resolved
Comparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysis.
Tripkovic L, Lambert H, Hart K, Smith CP, Bucca G, Penson S, Chope G, Hyppönen E, Berry J, Vieth R, Lanham-New S
pmid 22552031

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

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