Peptide Atlas · Small molecule

Creatine phosphate (phosphocreatine)

In a randomized, double-blind pilot trial in 120 high-risk valve-surgery patients, intravenous and cardioplegic phosphocreatine did not lower peak troponin I after surgery compared with saline, nor change creatinine, inotrope use or other secondary outcomes.

emerging

provisional
PubChem 9548602
2 citations
0 discussions
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Creatine phosphate sodium
Neoton
Phosphocreatine

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What the evidence says

six tiers, never blended

emerging — human data exists, and it is thin or contested

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- emerging
  Claim: Exogenous phosphocreatine did not reduce troponin release in high-risk cardiac surgery (pilot RCT) standing
- resolved
Myocardial protection with phosphocreatine in high-risk cardiac surgery patients: a randomized trial.
Lomivorotov V, Merekin D, Fominskiy E, Ponomarev D, Bogachev-Prokophiev A, Zalesov A, Cherniavsky A, Shilova A, Guvakov D, Lomivorotova L, Lembo R, Landoni G
pmid 38030971
- emerging
  Claim: Reduced myocardial phosphocreatine-to-ATP ratio predicts mortality in dilated cardiomyopathy standing
- resolved
Myocardial phosphocreatine-to-ATP ratio is a predictor of mortality in patients with dilated cardiomyopathy.
Neubauer S, Horn M, Cramer M, Harre K, Newell JB, Peters W, Pabst T, Ertl G, Hahn D, Ingwall JS, Kochsiek K
pmid 9337189

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Negative findings

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