Peptide Atlas · Vitamin

Cyanocobalamin

In a dose-finding trial in 120 older people with mild vitamin B12 deficiency, oral cyanocobalamin normalised the deficiency marker methylmalonic acid only at about 650 to 1,000 micrograms a day, over 200 times the recommended dietary allowance.

established

provisional
PubChem 165339223
2 citations
0 discussions
0 followers
CN-Cbl
Cobamin
Cyano-B12
Vitamin B12

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What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

Evidence, kept apart

The Atlas never mixes evidence types into one blob. Each claim below carries the tier it actually sits in; an unresolved citation is shown and does not move the page.

Evidence map for Cyanocobalamin. Tier reflects study design, not enthusiasm.
Claim	Tier	Source
Oral cyanocobalamin in pernicious anemia (open-label, n=10)	emerging	pmid 24672108
Oral cyanocobalamin dose needed to correct mild B12 deficiency in older people (RCT, n=120)	established	pmid 15911731

Unanswered questions

No open questions on file. Either everything about this molecule is known, or nobody has admitted what is not.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.