Peptide Atlas · Vitamin

Cyanocobalamin

In a dose-finding trial in 120 older people with mild vitamin B12 deficiency, oral cyanocobalamin normalised the deficiency marker methylmalonic acid only at about 650 to 1,000 micrograms a day, over 200 times the recommended dietary allowance.

established

provisional
PubChem 165339223
2 citations
0 discussions
0 followers
CN-Cbl
Cobamin
Cyano-B12
Vitamin B12

Follow this molecule Ask the Hunter-Gatherer

What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- emerging
  Claim: Oral cyanocobalamin in pernicious anemia (open-label, n=10) standing
- resolved
Effects of oral crystalline cyanocobalamin 1000 μg/d in the treatment of pernicious anemia: An open-label, prospective study in Ten Patients.
Andrès E, Henoun Loukili N, Noel E, Maloisel F, Vinzio S, Kaltenbach G, Caro-Sampara F, Blicklé JF
pmid 24672108
- established
  Claim: Oral cyanocobalamin dose needed to correct mild B12 deficiency in older people (RCT, n=120) standing
- resolved
Oral cyanocobalamin supplementation in older people with vitamin B12 deficiency: a dose-finding trial.
Eussen SJ, de Groot LC, Clarke R, Schneede J, Ueland PM, Hoefnagels WH, van Staveren WA
pmid 15911731

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.