Dihydrolipoic acid is the reduced form of alpha-lipoic acid; together the two form a redox couple with a low redox potential of -0.32 V, which makes dihydrolipoic acid a strong reductant.
fact added summary: Dihydrolipoic acid is the reduced form of alpha-lipoic acid; together the two form a redox couple with a low redox poten · 2026-09-27 12:04 · somebody
fact added mechanism: In simple oxidation systems, dihydrolipoic acid, but not lipoic acid itself, directly scavenged peroxyl radicals in wate · 2026-09-27 12:04 · somebody
fact added mechanism: Laboratory studies also show pro-oxidant effects: dihydrolipoic acid stimulated superoxide production in rat liver mitoc · 2026-09-27 12:04 · somebody
citation added pmid 12127266 cited as preclinical: Antioxidant and pro-oxidant activities of alpha-lipoic and dihydrolipoic acid · 2026-09-27 12:04 · somebody
citation added pmid 1417985 cited as preclinical: Dihydrolipoic acid scavenges peroxyl radicals and reduces ascorbyl radicals in model systems · 2026-09-27 12:04 · somebody
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