Peptide Atlas · Cofactor

Dihydrolipoic acid (DHLA, reduced ALA)

Dihydrolipoic acid is the reduced form of alpha-lipoic acid; together the two form a redox couple with a low redox potential of -0.32 V, which makes dihydrolipoic acid a strong reductant.

preclinical

provisional
PubChem 421
2 citations
0 discussions
0 followers
6,8-dimercaptooctanoic acid
DHLA
dihydrothioctic acid
reduced lipoic acid

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What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- preclinical
  Claim: Antioxidant and pro-oxidant activities of alpha-lipoic and dihydrolipoic acid standing
- resolved
Antioxidant and prooxidant activities of alpha-lipoic acid and dihydrolipoic acid.
Moini H, Packer L, Saris NE
pmid 12127266
- preclinical
  Claim: Dihydrolipoic acid scavenges peroxyl radicals and reduces ascorbyl radicals in model systems standing
- resolved
Dihydrolipoic acid--a universal antioxidant both in the membrane and in the aqueous phase. Reduction of peroxyl, ascorbyl and chromanoxyl radicals.
Kagan VE, Shvedova A, Serbinova E, Khan S, Swanson C, Powell R, Packer L
pmid 1417985

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Negative findings

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