Peptide Atlas · Peptide

Humanin

Humanin is an anti-apoptotic peptide of 24 amino acids; an identical open reading frame exists in the mitochondrial genome, and the mitochondrial version also binds and suppresses the cell-death protein Bax.

preclinical

provisional
PubChem 16131438
2 citations
0 discussions
0 followers
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Humanin (wild-type)

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What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

Evidence, kept apart

The Atlas never mixes evidence types into one blob. Each claim below carries the tier it actually sits in; an unresolved citation is shown and does not move the page.

Evidence map for Humanin. Tier reflects study design, not enthusiasm.
Claim	Tier	Source
Humanin suppresses apoptosis by interfering with Bax activation	preclinical	pmid 12732850
Humanin as the first mitochondrial-derived peptide	preclinical	pmid 23402768

Unanswered questions

No open questions on file. Either everything about this molecule is known, or nobody has admitted what is not.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.