Peptide Atlas · Peptide

Humanin

Humanin is an anti-apoptotic peptide of 24 amino acids; an identical open reading frame exists in the mitochondrial genome, and the mitochondrial version also binds and suppresses the cell-death protein Bax.

preclinical

provisional
PubChem 16131438
2 citations
0 discussions
0 followers
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Humanin (wild-type)

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What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 2 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

- preclinical
  Claim: Humanin suppresses apoptosis by interfering with Bax activation standing
- resolved
Humanin peptide suppresses apoptosis by interfering with Bax activation.
Guo B, Zhai D, Cabezas E, Welsh K, Nouraini S, Satterthwait AC, Reed JC
pmid 12732850
- preclinical
  Claim: Humanin as the first mitochondrial-derived peptide standing
- resolved
Humanin: a harbinger of mitochondrial-derived peptides?
Lee C, Yen K, Cohen P
pmid 23402768

A claim's standing is its latest row in an append-only history; a tombstone names the later evidence and the reason. The Graveyard and the Resurrection Yard.

Negative findings

failure is information

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