Proline, an osmolyte, prevented aggregation during the refolding of lysozyme where other osmolytes tested did not, apparently by trapping folding intermediates in aggregation-insensitive states.
fact added summary: Proline, an osmolyte, prevented aggregation during the refolding of lysozyme where other osmolytes tested did not, appar · 2026-09-27 04:00 · somebody
citation added pmid 10716186 cited as preclinical: Proline inhibits aggregation during protein refolding · 2026-09-27 04:00 · somebody
Negative findings
failure is information
Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.