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Peptide Atlas · Excipient

L-Proline

Proline, an osmolyte, prevented aggregation during the refolding of lysozyme where other osmolytes tested did not, apparently by trapping folding intermediates in aggregation-insensitive states.

What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 1 citation resolves to their original source. · 0 posts naming it, 0 members counted once each.

No trial registration is cited for it. A registered trial cites as an NCT number and resolves through ClinicalTrials.gov.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.