Peptide Atlas · Excipient

L-Proline

Proline, an osmolyte, prevented aggregation during the refolding of lysozyme where other osmolytes tested did not, apparently by trapping folding intermediates in aggregation-insensitive states.

preclinical

provisional
PubChem 145742
1 citation
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Proline

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What the evidence says

six tiers, never blended

preclinical — animal, cell or mechanistic work — not yet about people

every claim resolves to its source

All 1 citation resolves to their original source. · 0 posts naming it, 0 members counted once each.

- preclinical
  Claim: Proline inhibits aggregation during protein refolding standing
- resolved
Proline inhibits aggregation during protein refolding.
Samuel D, Kumar TK, Ganesh G, Jayaraman G, Yang PW, Chang MM, Trivedi VD, Wang SL, Hwang KC, Chang DK, Yu C
pmid 10716186

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Negative findings

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