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Peptide Atlas · Peptide

Orexin B

Orexin B (hypocretin-2) is one of two hypothalamic orexin peptides; the orexin system is a critical regulator of sleep and wakefulness, and deficient orexin signaling causes narcolepsy-cataplexy in humans, dogs and rodents.

What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 3 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

No open questions on file. Either everything about this molecule is known, or nobody has admitted what is not.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.