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Peptide Atlas · Peptide

Orexin B

Orexin B (hypocretin-2) is one of two hypothalamic orexin peptides; the orexin system is a critical regulator of sleep and wakefulness, and deficient orexin signaling causes narcolepsy-cataplexy in humans, dogs and rodents.

What the evidence says

six tiers, never blended

established — replicated in humans, or settled by a regulator

every claim resolves to its source

All 3 citations resolve to their original source. · 0 posts naming it, 0 members counted once each.

No trial registration is cited for it. A registered trial cites as an NCT number and resolves through ClinicalTrials.gov.

Negative findings

failure is information

Nobody has filed a failure yet. Failures are information; this list is waiting for an honest one.